So if you’re like me and now have become tranq bitch on Lich King, here’s a macro that may help you out:
#showtooltip Soothe/use [@mouseover,harm][@focus,harm]Soothe
This macro will prioritize mouseover, then focus, then target. This will allow you to focus one shambling and still potentially tranq the other by mousing over it. If you don’t have a mouseover or a focus, it’ll tranq your current target.
I also use the following macro to set my focus. It’ll attempt to focus the mouseover target, and if you don’t have one, will focus your current target.